Research Laboratories
Multi-User Labs
1. PPQQ Multi-User Analytics Center (Multi-User Analytics Center service site)
Located in rooms 38A and 38B of the Chemistry Department, it contains numerous multi-user equipment that were purchased with resources from financial bodies (FAPERJ, CNPQ, CAPES, FINEP, etc.). This space currently has: Bruker 400 and 500MHz NMR, Bruker FTIR-Vertex 70, Gas chromatograph coupled to mass spectrometry (Shimadzu) and CG-FID 5890, Series II (Agilent), HPLC-DAD (Prominence-Shimadzu), Circular dichroism spectropolarimeter J-818 (Jasco), Digital polarimeter P-2000 (Jasco), Lyophilizer (Liotop) and Chamelon Plate Reader (Hydex), ChemDoc Image Digitizer (Bio-Rad), Raman (Bruker) and Isolera Four FLASH Chromatography System (Biotage). Part of this equipment (RMN, CGMS, CG-FID) is maintained by UPS (UPS), which function as a secondary electrical energy supply system and maintain the operation of the equipment when there is an interruption in the primary energy supply. In addition to the UPS, there is a 55KVa generator to provide emergency electrical energy when there is a power outage. The multi-user equipment allocated to the Analytical Center has provided analytical support for the development of students’ theses and dissertations, has allowed the execution of an articulated set of lines of research from the different stricto sensu Postgraduate Programs at UFRRJ, as well as supporting the research activities of other institutions.
2. Laboratory of Oxidative Stress in Microorganisms – LEOM (Multi-User Laboratory)
This laboratory, located in room 24 of the Chemistry Pavilion, carries out research with microorganisms using equipment designed for this purpose; such as horizontal laminar flow hood (HEPA filter), refrigerated shaker-type incubator with controlled temperature and agitation, UV/Vis spectrophotometer (200-1000nm), refrigerated (-4 °C) and non-refrigerated centrifuges for tubes (15mL and 50mL) of the falcon type, centrifuge for microtubes (1.5mL), microscope with objectives of 40, 100 and 400X, temperature-controlled water bath, temperature-controlled BOD oven, refrigerator and freezer, drying oven for materials, autoclave for sterilization of cultivation media and materials, vortex tube agitators, analytical and semi-analytical balance, stirring plate, microwave, pH meter, among others, occupying a total area of approximately 12m², with a useful area of approximately 8m².
3. Natural Bioactive Chemistry Laboratory – LQBION (Multi-User Laboratory)
LQBION, coordinated by Professor Douglas Siqueira de Almeida Chaves, has been operating at UFRRJ since 2011, developing scientific research related to the projects: a) study of essential oils and their applications in veterinary medicine (insect and mite control); b) essential oils and applications in the agronomic field; c) studies of natural products of animal origin; d) Natural products from native mushrooms. LQBioN has had a good production in the last five years, with 40 works (JCR=32,485), with emphasis on fundraising involving the study of Natural Products, having been awarded IC grants, FAPERJ, MEC and CNPq notices. At an international level, it maintains a formalized partnership between student missions and the LQBioN coordinator with the group from the Institute of the Polish Academy of Sciences (Poland) and the National Autonomous University of Mexico. It has the following equipment: 1 – UPLC//Jasco; 2 – CLAE/Shimadzu; 3 – Milliq/Merck; 4 – Elisa/Thermo reader; 5 – Freeze dryer/LioBras; 6 – Ultraviolet/Even; 7 – Greenhouse with Air Renewal. Has expertise in the study of essential oils and fixed components applied to veterinary medicine. LQBioN has partnerships with companies in the propolis and essential oils sector; Currently a partnership with Canapse is underway for cannabis studies.
Restricted Use Laboratories
4. Laboratory of Molecular Diversity and Medicinal Chemistry – LaDMol-QM
LaDMol-QM is coordinated by Professor Arthur Eugen Kummerle. The laboratory’s research activities are focused on Medicinal Chemistry, aiming at the discovery and development of new bioactive compounds, candidates for new drugs with therapeutic potential in various diseases, and also on the Organic Synthesis of heterocycle compounds.
5. Chemical Kinetics Laboratory – LCQ
The LCQ is coordinated by Professor Glauco Favilla Bauerfeldt and is located in room 41 of the Chemistry Pavilion. It has the following resources: twelve machines with I7 processors (in total 8, 12 or 24 processors each), with 8 to 48 Gb of memory and 1 to 4 TB of disk. These machines were purchased with FAPERJ resources, as well as two deskjet printers (Epson Stylus TX125 and HP Officejet 4500 G510A) and three laser printers (Canon 1120, Samsung SCX-4100 and HP laserjet P3015). These resources are intended for processing ab initio calculations and chemical kinetics and dynamics calculations with the aim of developing potential energy surfaces to support the research of the Chemical Kinetics Research Group and other research groups in scientific cooperation projects.
6. Molecular Modeling Laboratory
The Molecular Modeling Laboratory is located in room 44 (2nd floor) of the UFRRJ Chemistry Institute (LabMol-UFRRJ) and has the following dedicated infrastructure for carrying out computational calculations:
01 HP Proliant ML 350 Gen9 Workstation, Intel Xeon CPU E5-2630 v4 @ 2.20 GHz x 40, HD 2.0 TB, RAM: 32.0 GB
01 HP Proliant ML 350p Gen8 Workstation, Intel Xeon CPU E5-2620 v2 @ 2.10 GHz x 12, HD 1.9 TB, RAM: 32.0 GB
01 HP Z2 Workstation, Intel(R) Xeon(R) W-1270 CPU @ 3.40 GHz 3.41 GHz, HD: 512 GB, RAM: 32.0 GB
01 Dell Precision Workstation, Intel Core i7 CPU 940@ 2.93 GHz 2.93 GHz, HD 512 GB, RAM: 16.0 GB
01 Dell Precision 3660 Workstation, Intel Core i5-12500, 3.0 GHz, SSD 512 GB, RAM: 32.0 GB.
Among the installed programs, we highlight the MOPAC2016 Program, used in semi-empirical quantum calculations of large molecular systems, such as proteins and their interaction complexes, the molecular docking program GOLD 2023.2.0, the molecular modeling program Spartan’24, for calculations with ab initio models, density functional, post-Hartree-Fock (CI and MPn) and thermochemical calculations G3(MP2), G3, G4 and T1, in addition to spectra prediction models and modules for accelerated calculations based on neural networks, and the Origin2022 program, for analysis and development of statistical models, as well as others for visualization and analysis of molecular structures.
7. Natural Products Chemistry Research Laboratory (LQPN)
The Research Laboratory in Chemistry of Natural Products – LQPN is coordinated by Professors Marcia Cristina Campos de Oliveira and Luciano Ramos Suzart. Located in room 55 of the Chemistry Pavilion, it is a restricted-use research laboratory with the main research target being the chemistry of natural products in its entirety. Since its inception, research projects have been developed around the chemistry of natural products, with an emphasis on: phytochemistry, natural products and biological activity, qualitative and quantitative determination of natural products, polymers associated with natural products, quality control of medicines and cosmetics, forensic and environmental analysis. Following these characteristics, the LQPN has housed, in an interdisciplinary space, several related research groups, in which professors from IQ and other higher education and research institutions participate, as well as researchers in training, distributed between Scientific Initiation and Postgraduate Students and also in projects that aim to prepare Course Completion Works (TCC- monographs and technical reports). The professors who, to this day, are responsible for the LQPN have made efforts to maintain the laboratory’s work logistics, which includes operational infrastructure, since the scientific activities carried out there require resources and technologies aimed at obtaining results. In addition to the activities mentioned above, LQPN has promoted academic events open to high school communities through extension projects presented during the SNCTs. The main projects developed in this laboratory are:
1. PHYTOCHEMICAL EVALUATION AND BIOLOGICAL ACTIVITY OF NON-CONVENTIONAL FOOD PLANTS AND SEA ALGAE
2. SYNTHESIS OF ACRYLIC POLYMERS ASSOCIATED WITH NATURAL PRODUCTS
3. CHEMICAL STUDIES OF PLANT SPECIES FROM BRAZILIAN BIODIVERSITY
4. APPLIED ANALYTICAL CHEMISTRY WITH A FOCUS ON QUALITY CONTROL AND FORENSIC AND ENVIRONMENTAL MONITORING
8. Laboratory of Aromatic and Medicinal Plants (LABPAN)
LabPAM was created with the purpose of serving the development of academic activities, mainly basic and applied research involving aromatic and medicinal plants. It is coordinated by Professor Marco André Alves de Souza. Its activities are conducted with a focus on prospecting plant species and natural products, mainly essential oils, and developing biotechnological applications useful for the agricultural sector. The laboratory has its own structure and support from Research Groups in different areas of knowledge, such as agronomy, biology, chemistry, pharmacy and veterinary.
9. Nanotechnology, Ceramics and Composites Laboratory – LNanoC2
LNanoC2 is located in the Department of Chemical Engineering at UFRRJ. The Laboratory has materials and equipment for the development and characterization of nanostructured materials for application in different areas of knowledge. The main equipment of LNanoC2 are: Gas exhaust hood; UV-vis spectrophotometer; Analytical balances, Vacuum pump, Ultrasonicator; Turrax, Potentiostat; Drying oven; Ultrasound bath; Heating and stirring plates; Shaker; 3D printer, Filament extrusion system.
Externally to LNanoC2, the group has the structure available in the other laboratories that are part of the group, such as the Interface Phenomena Engineering Laboratory (LABEFIT – PEQ/COPPE/UFRJ), Chemical Kinetics Laboratory (LCQ – IQ/UFRRJ), Biomaterials Laboratory (LabBioMat – DEQ/UFRRJ) and Food Analysis and Chemistry Laboratory (DTA/UFRRJ).
10. Analytical and Environmental Chemistry Research Laboratory – LPQA
The LPQA is coordinated by Professor José Geraldo Rocha Junior and is located in rooms 11 and 16B (total area 55 m²) of the Chemistry Pavilion. The research group has worked on the development of simple and low-cost analytical methods for the study of different matrices such as biodiesel, soils, metallic alloys and industrial effluents. It has the following infrastructure: 1. K37-VIS KASVI Visible Spectrophotometer; 2. KF-1000 ANALYSER Titrator; 3. Analytical Balance 0.0001g ATX224R SHIMADZ; 4. Heating plate with stirring 10L Ceramic 220V HS7 IKA; 5. Dell Vostro 3710 Microcomputer (Core i5-12400, RAM 8GB, SSD 256GB); 6. UPS Apc Back Ups 1200va/600w; 7. TECNAL TE-184 Thermostatic Bath (± 0.1°C); 8. GOLANDER BT100F Digital Peristaltic Pump; 9. BELL Analytical Balance 0.05 g; 10. Refracto® 30GS Digital Portable Refractometer; 11. FISATOM 713D Mechanical Stirrer; 12. Ultrasonic bath; 13. ANALYSER flame photometer; 14. Portable pH meters; 15. Vortex shaker; 16. Refrigerator; 17. Centrifuge; 18. Heating blankets; 19. Bain Marie.
Other research laboratories
There are also several other research laboratories incorporated into the PPGQ infrastructure and dedicated to the development of experimental research work by teachers and students:
Laboratory of Photochemistry
Research Laboratory of Analytical Chemistry
Laboratory of Medicinal Chemistry
Laboratory of Honey Chemistry
Laboratory of Natural Products
Laboratory of Inorganic Synthesis
Laboratory of Organic Synthesis
Infrastructure
The PPGQ has two classrooms (Prof. Otto Gotlieb Room – 50 seats and Room 49 with 20 seats) with TV sets and datashow equipment in both rooms, for classes, seminars and defenses of dissertations/theses and defenses in a hybrid format. There is a Wi-Fi network that serves rooms 49 and 50 and a Wi-Fi network that serves the secretariat, teaching staff and PPGQ students. In addition to these rooms, the PPGQ has a secretariat where the coordinator and an outsourced secretary work and administrative activities for the operation of the PPGQ are carried out and a mezzanine.
