{"id":2618,"date":"2017-11-22T11:40:44","date_gmt":"2017-11-22T14:40:44","guid":{"rendered":"http:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/?page_id=2618"},"modified":"2017-11-22T11:40:44","modified_gmt":"2017-11-22T14:40:44","slug":"ic-1347","status":"publish","type":"page","link":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1347\/","title":{"rendered":"IC-1347 – Qu\u00edmica Biol\u00f3gica"},"content":{"rendered":"

4 cr\u00e9ditos 60 horas te\u00f3ricas<\/strong><\/p>\n

 <\/p>\n

OBJETIVOS<\/strong>:<\/p>\n

Introduzir aos alunos conceitos de rea\u00e7\u00f5es qu\u00edmicas nos seres vivos<\/p>\n

 <\/p>\n

EMENTA<\/strong>:<\/p>\n

1. Aspectos cin\u00e9ticos e termodin\u00e2micos das rea\u00e7\u00f5es qu\u00edmicas.<\/p>\n

2. \u00c1cidos e bases.<\/p>\n

3. Estereoqu\u00edmica<\/p>\n

4. Rea\u00e7\u00f5es org\u00e2nicas: Introdu\u00e7\u00e3o aos mecanismos envolvendo o metabolismo<\/p>\n

5. Cat\u00e1lise<\/p>\n

 <\/p>\n

CONTE\u00daDO PROGRAM\u00c1TICO:<\/strong><\/p>\n

1. Aspectos cin\u00e9ticos e termodin\u00e2micos das rea\u00e7\u00f5es qu\u00edmicas<\/p>\n

1.1. Liga\u00e7\u00f5es qu\u00edmicas<\/p>\n

1.2. Estequiometria e molecularidade;<\/p>\n

1.3. Velocidade e ordem de rea\u00e7\u00e3o;<\/p>\n

1.4. Medidas cin\u00e9ticas experimentais;<\/p>\n

1.5. Termodin\u00e2mica: entalpia, entropia, energia livre;<\/p>\n

1.6. Estado de transi\u00e7\u00e3o: DG\u00b9<\/p>\n

1.7. Princ\u00edpio da reversibilidade microsc\u00f3pica;<\/p>\n

1.8. Interpreta\u00e7\u00e3o dos par\u00e2metros termodin\u00e2micos;<\/p>\n

1.9. Controle cin\u00e9tico versus controle termodin\u00e2mico.<\/p>\n

2. \u00c1cidos e bases<\/p>\n

2.1. Conceitos fundamentais<\/p>\n

2.2. Efeitos estruturais<\/p>\n

3. Estereoqu\u00edmica<\/p>\n

3.1. Geometria molecular; estereoisomerismo, Proje\u00e7\u00f5es de Fisher e Newman.<\/p>\n

3.2 .Is\u00f4mero conformacional: an\u00e1lise conformacional de compostos c\u00edclicos e<\/p>\n

ac\u00edclicos.<\/p>\n

3.3. Is\u00f4mero Configuracional: Isomeria \u00f3ptica; Quiralidade; proquiralidade; resolu\u00e7\u00e3o<\/p>\n

de enantiom\u00earos.<\/p>\n

4. Rea\u00e7\u00f5es org\u00e2nicas: Introdu\u00e7\u00e3o aos mecanismos envolvendo o metabolismo<\/p>\n

3.1. Principais mecanismos: SN alif\u00e1tica e arom\u00e1tica; SE arom\u00e1tica; adi\u00e7\u00e3o a liga\u00e7\u00f5es<\/p>\n

m\u00faltiplas e C-hetero\u00e1tomo; via intermedi\u00e1rios radicalares<\/p>\n

3.2. Tipos de rea\u00e7\u00f5es;<\/p>\n

3.3. M\u00e9todos empregados na determina\u00e7\u00e3o dos mecanismos de rea\u00e7\u00e3o.<\/p>\n

4. Cat\u00e1lise<\/p>\n

4.1. Cat\u00e1lise \u00e1cida e b\u00e1sica;<\/p>\n

4.2. Cat\u00e1lise via liga\u00e7\u00f5es n\u00e3o-covalentes: micelar e CTF;<\/p>\n

4.3. Cat\u00e1lise heterog\u00eanea<\/p>\n

4.4. Cat\u00e1lise enzim\u00e1tica.<\/p>\n

 <\/p>\n

BIBLIOGRAFIA<\/strong>:<\/p>\n

1. \u201cQu\u00edmica Org\u00e2nica Avanzada\u201d, Paloma Ballesteros Garc\u00eda, Rosa M. Claramunt<\/p>\n

Vallesp\u00ed, Dionisia Sanz del Castillo e Enrique Teso Vilar, Editora da Universidad<\/p>\n

Nacional de Educaci\u00f3n a Distancia (UNED), Madrid, 2001.<\/p>\n

2.\u201cChemistry of Biomolecules: An Introduction\u201d, R. J. SimmondsRoyal Society of<\/p>\n

Chemistry, Cambridge, 1992.<\/p>\n

3.Dey, P.M.; Harborne, J.B. Plant Biochemistry. Acad. Press. 1997. 554 p.<\/p>\n

4. Nelson, D. e Cox, M. Princ\u00edpios de Bioqu\u00edmica do Lehninger. Sarvier. 2006.4\u00aa Ed.<\/p>\n

5. Voet, B., Voet, J.G. Pratt, C. Fundamentos de Bioqu\u00edmica. ArtMed. 2004.<\/p>\n

6. Essentials of Organic Chemistry. For students of pharmacy, medicinal chemistry and<\/p>\n

biological chermistry. Paul M. Dewick. John Wiley & Sons Ltda. 2006.<\/p>\n

7. Biochemistry \u2013The Chemical Reactions of Living Cells. Volumes 1 e 2. 2nd. David<\/p>\n

E. Metzler.Elsevier Academic Press. 2001<\/p>\n","protected":false},"excerpt":{"rendered":"

4 cr\u00e9ditos 60 horas te\u00f3ricas   OBJETIVOS: Introduzir aos alunos conceitos de rea\u00e7\u00f5es qu\u00edmicas nos seres vivos   EMENTA: 1. … <\/i><\/a><\/p>\n","protected":false},"author":29,"featured_media":0,"parent":20,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_themeisle_gutenberg_block_has_review":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2618","page","type-page","status-publish","hentry"],"yoast_head":"\nIC-1347 - Qu\u00edmica Biol\u00f3gica - Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1347\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"IC-1347 - Qu\u00edmica Biol\u00f3gica - Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica\" \/>\n<meta property=\"og:description\" content=\"4 cr\u00e9ditos 60 horas te\u00f3ricas   OBJETIVOS: Introduzir aos alunos conceitos de rea\u00e7\u00f5es qu\u00edmicas nos seres vivos   EMENTA: 1. ...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1347\/\" \/>\n<meta property=\"og:site_name\" content=\"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. tempo de leitura\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/atividades-disciplinares\\\/ic-1347\\\/\",\"url\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/atividades-disciplinares\\\/ic-1347\\\/\",\"name\":\"IC-1347 - Qu\u00edmica Biol\u00f3gica - Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/#website\"},\"datePublished\":\"2017-11-22T14:40:44+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/atividades-disciplinares\\\/ic-1347\\\/#breadcrumb\"},\"inLanguage\":\"pt-BR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/atividades-disciplinares\\\/ic-1347\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/atividades-disciplinares\\\/ic-1347\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"In\u00edcio\",\"item\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Lista de Disciplinas\",\"item\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/atividades-disciplinares\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"IC-1347 – Qu\u00edmica Biol\u00f3gica\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/#website\",\"url\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/\",\"name\":\"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"pt-BR\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"IC-1347 - Qu\u00edmica Biol\u00f3gica - Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1347\/","og_locale":"pt_BR","og_type":"article","og_title":"IC-1347 - Qu\u00edmica Biol\u00f3gica - Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica","og_description":"4 cr\u00e9ditos 60 horas te\u00f3ricas   OBJETIVOS: Introduzir aos alunos conceitos de rea\u00e7\u00f5es qu\u00edmicas nos seres vivos   EMENTA: 1. ...","og_url":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1347\/","og_site_name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica","twitter_card":"summary_large_image","twitter_misc":{"Est. tempo de leitura":"2 minutos"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1347\/","url":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1347\/","name":"IC-1347 - Qu\u00edmica Biol\u00f3gica - Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica","isPartOf":{"@id":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/#website"},"datePublished":"2017-11-22T14:40:44+00:00","breadcrumb":{"@id":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1347\/#breadcrumb"},"inLanguage":"pt-BR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1347\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1347\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"In\u00edcio","item":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/"},{"@type":"ListItem","position":2,"name":"Lista de Disciplinas","item":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/"},{"@type":"ListItem","position":3,"name":"IC-1347 – Qu\u00edmica Biol\u00f3gica"}]},{"@type":"WebSite","@id":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/#website","url":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/","name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"pt-BR"}]}},"acf":[],"_links":{"self":[{"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/pages\/2618","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/users\/29"}],"replies":[{"embeddable":true,"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/comments?post=2618"}],"version-history":[{"count":1,"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/pages\/2618\/revisions"}],"predecessor-version":[{"id":2619,"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/pages\/2618\/revisions\/2619"}],"up":[{"embeddable":true,"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/pages\/20"}],"wp:attachment":[{"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/media?parent=2618"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}