{"id":2562,"date":"2017-11-22T09:22:11","date_gmt":"2017-11-22T12:22:11","guid":{"rendered":"http:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/?page_id=2562"},"modified":"2025-03-28T09:56:40","modified_gmt":"2025-03-28T12:56:40","slug":"ic-1301","status":"publish","type":"page","link":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1301\/","title":{"rendered":"IC-1301 \u2013 Isolamento e Purifica\u00e7\u00e3o de Subst\u00e2ncias Org\u00e2nicas"},"content":{"rendered":"

3 Credits 45 Practical hours<\/strong><\/p>\n

OBJECTIVES: Allow the student to know and apply analytical techniques for the<\/p>\n

isolation and purification of natural and synthetic substances.<\/p>\n

SUMMARY:<\/p>\n

1. Chromatographic Methods (14 hours).<\/p>\n

2. Extraction, Separation and Purification Methods (16 hours)<\/p>\n

3. Isolation and Purification of Organic Substances.<\/p>\n

4. Reactions to characterize functional groups (16 hours)<\/p>\n

PROGRAM CONTENT:<\/strong><\/p>\n

01. Chromatographic Methods<\/p>\n

Chromatography (introduction): Mechanisms of adsorption, partition, ion exchange and exclusion.<\/p>\n

Open column chromatography, analytical and preparative thin layer, paper. Types and Recovery<\/p>\n

of adsorbents.<\/p>\n

02. Introduction to gas chromatography, high performance liquid chromatography and introduction to<\/p>\n

counter current chromatography.<\/p>\n

03. Extraction, Separation and Purification methods applied to organic substances.<\/p>\n

Liquid-liquid extraction, Soxhlet extraction, acid-base extraction. Crystallization. Sublimation.<\/p>\n

04. Chemical Characterization: Functional Groups and Classes of Natural Products<\/p>\n

05. Structural modifications to organic substances.<\/p>\n

Reactions: Oxidation, reduction, methylation, demethylation, acetylation, hydrolysis, ketal formation, esterification<\/p>\n

BIBLIOGRAPHY:<\/strong><\/p>\n

1. \u201cIntroduction to Experimental Phytochemistry\u201d – F.J. Abreu Matos, UFCE, Fortaleza, CE, 1980.<\/p>\n

\u201cPrinciples and Practice of Modern Chromatographic Methods\u201d \u2013 K. Robards, P.R. Haddad, P.E.<\/p>\n

Jackson, Academic Press, Harcourt Brace & Company, Publishers, London, 1997.<\/p>\n

2. \u201cPractice of Thin Layer Chromatography\u201d – J.C. Touchstone and M.F. Dobbins, John Wiley &<\/p>\n

Sons, New York, USA, 1983.<\/p>\n

3. \u201cIntroduction to Chromatographic Methods\u201d – C.H. Collins and G.L. Braga, Ed. from UNICAMP,<\/p>\n

Campinas, SP, 1988.<\/p>\n

4. \u201cReactions and Synthesis in the Organic Chemistry Laboratory\u201d – L.F. Tietze and T. Eicher,<\/p>\n

Springer Verlag, Germany, 1988.<\/p>\n

5. Textbook of Practical Organic Chemistry\u201d \u2013 A. I. Vogel – B. S. Furniss; A. J. Hannaford; P. W.<\/p>\n

G. Smith and A. R. Tatchell. Longman Scientific & Technical. 5th Ed.1991.<\/p>\n

6. \u201cM\u00e9todos de Investigaci\u00f3n Fitoqu\u00edmica\u201d, Jorge A. Dominguez, Limusa, M\u00e9xico, 1973.<\/p>\n

7. Phytochemical Methods. A guide to Modern Techniques of Plant Analysis. J.B. Harborne,<\/p>\n

Chapman and Hall, London. 1973.<\/p>\n","protected":false},"excerpt":{"rendered":"

3 Credits 45 Practical hours OBJECTIVES: Allow the student to know and apply analytical techniques for the isolation and purification … <\/i><\/a><\/p>\n","protected":false},"author":29,"featured_media":0,"parent":20,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_themeisle_gutenberg_block_has_review":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2562","page","type-page","status-publish","hentry"],"yoast_head":"\nIC-1301 \u2013 Isolamento e Purifica\u00e7\u00e3o de Subst\u00e2ncias Org\u00e2nicas - Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1301\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"IC-1301 \u2013 Isolamento e Purifica\u00e7\u00e3o de Subst\u00e2ncias Org\u00e2nicas - Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica\" \/>\n<meta property=\"og:description\" content=\"3 Credits 45 Practical hours OBJECTIVES: Allow the student to know and apply analytical techniques for the isolation and purification ...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1301\/\" \/>\n<meta property=\"og:site_name\" content=\"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica\" \/>\n<meta property=\"article:modified_time\" content=\"2025-03-28T12:56:40+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. tempo de leitura\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/atividades-disciplinares\\\/ic-1301\\\/\",\"url\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/atividades-disciplinares\\\/ic-1301\\\/\",\"name\":\"IC-1301 \u2013 Isolamento e Purifica\u00e7\u00e3o de Subst\u00e2ncias Org\u00e2nicas - Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/#website\"},\"datePublished\":\"2017-11-22T12:22:11+00:00\",\"dateModified\":\"2025-03-28T12:56:40+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/atividades-disciplinares\\\/ic-1301\\\/#breadcrumb\"},\"inLanguage\":\"pt-BR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/atividades-disciplinares\\\/ic-1301\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/atividades-disciplinares\\\/ic-1301\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"In\u00edcio\",\"item\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Lista de Disciplinas\",\"item\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/atividades-disciplinares\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"IC-1301 \u2013 Isolamento e Purifica\u00e7\u00e3o de Subst\u00e2ncias Org\u00e2nicas\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/#website\",\"url\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/\",\"name\":\"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/cursos.ufrrj.br\\\/posgraduacao\\\/ppgq\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"pt-BR\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"IC-1301 \u2013 Isolamento e Purifica\u00e7\u00e3o de Subst\u00e2ncias Org\u00e2nicas - Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1301\/","og_locale":"pt_BR","og_type":"article","og_title":"IC-1301 \u2013 Isolamento e Purifica\u00e7\u00e3o de Subst\u00e2ncias Org\u00e2nicas - Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica","og_description":"3 Credits 45 Practical hours OBJECTIVES: Allow the student to know and apply analytical techniques for the isolation and purification ...","og_url":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1301\/","og_site_name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica","article_modified_time":"2025-03-28T12:56:40+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. tempo de leitura":"1 minuto"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1301\/","url":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1301\/","name":"IC-1301 \u2013 Isolamento e Purifica\u00e7\u00e3o de Subst\u00e2ncias Org\u00e2nicas - Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica","isPartOf":{"@id":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/#website"},"datePublished":"2017-11-22T12:22:11+00:00","dateModified":"2025-03-28T12:56:40+00:00","breadcrumb":{"@id":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1301\/#breadcrumb"},"inLanguage":"pt-BR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1301\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/ic-1301\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"In\u00edcio","item":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/"},{"@type":"ListItem","position":2,"name":"Lista de Disciplinas","item":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/atividades-disciplinares\/"},{"@type":"ListItem","position":3,"name":"IC-1301 \u2013 Isolamento e Purifica\u00e7\u00e3o de Subst\u00e2ncias Org\u00e2nicas"}]},{"@type":"WebSite","@id":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/#website","url":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/","name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Qu\u00edmica","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"pt-BR"}]}},"acf":[],"_links":{"self":[{"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/pages\/2562","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/users\/29"}],"replies":[{"embeddable":true,"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/comments?post=2562"}],"version-history":[{"count":5,"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/pages\/2562\/revisions"}],"predecessor-version":[{"id":7770,"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/pages\/2562\/revisions\/7770"}],"up":[{"embeddable":true,"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/pages\/20"}],"wp:attachment":[{"href":"https:\/\/cursos.ufrrj.br\/posgraduacao\/ppgq\/wp-json\/wp\/v2\/media?parent=2562"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}